Sergio Aguero has been ruled out of Manchester City’s Premier League opener against Wolves on Monday.
City’s record goalscorer missed the end of last season after knee surgery and is not yet back in full training.
“He still did not make one training session with us,” said City manager Pep Guardiola.
Defender Aymeric Laporte is also unlikely to feature at Molineux after testing positive for Covid-19 earlier this month.
Laporte was one of two players City reported had tested positive for coronavirus along with Riyad Mahrez.
Guardiola said: “Riyad came back three or four days ago. He is training but today (Friday) was the first day that Aymeric Laporte came back to us.
“I think Riyad will be available but Laporte not yet.”